I want to write this because I’ve seen a lot of questions on here that are from high schoolers ect.

DMSO can carry what it contains through your skin. It’s a fantastic solvent and that’s why that’s a concern. It’s a seemingly harmless thing to handle but its polarity makes it uniquely good at getting into your body. ((It takes what’s in it with it.)) things like essential oil on your fingers no big deal. Mix that amount of oil in DMSO and then skin contact and you have a toxicity problem. <<Don’t trust YouTubers cavalier attitude.>>

Long winded way to say, in chemistry it’s very easy to get in way over your head very fast. DMSO is not special in its hidden risk. Be careful out there.

Here’s a molecular dynamics simulation I ran of semaglutide, the active ingredient in Ozempic, bound to the GLP-1 receptor.

This is a 100-nanosecond molecular dynamics simulation showing how the peptide and receptor move and interact over time. Unlike a static crystal structure, MD allows us to observe protein flexibility, ligand motion, and changes in the binding environment.

GLP-1 receptor activation plays an important role in insulin secretion, appetite regulation, and blood glucose control, making it a major therapeutic target for type 2 diabetes and obesity.

The video is generated from my actual MD trajectory, not an AI-generated animation. It’s a visualization of the molecular motion predicted during the simulation, rather than a direct recording of molecules.

Thought this community might enjoy seeing what a drug–receptor complex looks like in motion!

We always harp on the chemical inaccuracies in shows and film, etc. But what are some examples of chemically accurate depictions of science and chemistry in media?

One that immediately comes to mind for me is The Martian scene where Matt Damon’s character is trying to create water using 2H2 + O2 —> 2H2O. Even the exothermic explosion part was reasonably accurate.

At work we mix lime and caustic (sodium hydroxide) into water at a 4:1 ratio to increase ph in our drilling fluid. A full barrel (205L roughly) at 15 degrees Celsius will heat up to as high as 85 degrees Celsius with one bag of caustic. I got my hands on a thermal imaging camera to see the process but I caught something more interesting. You’ll see in the thermal image that the caustic beads go in cold but heat up substantially when they hit the water/lime mixture.

it's a plastic windowsill that had been covered with transparent pies of soft cover and a some foamy cover. to prevent water spill from my plants so it wouldn't stain the windowsill. i suspect it has something to do with lighting. nover heard about plastic that changes calor in the dark

Hello mad scientists. I an making an artpiece for which I want to use thin aluminum dragon scales. I want said scales to look quite withered and to do so, I am looking for a pit effect.

My question is, how do I actually do this? I have been thinking of using a saltbath with hydrogenperoxide mixed in, but I fear that that will give quite an extreme reaction once the protective layer of the aluminum has been affected.

I would absolutely love some help and if this isnt the right place to ask this sort of thing, please tell me.

Many thanks in advance!

I found some old chemical equipment. Does anyone know what this equipment is called? The company is BoralPula.

What evidence is there that it is or not. People often try to get BPA free. Apparently health agencies and independent scientists remain divided on whether everyday exposure levels cause significant harm in humans.

Hi everyone,

we’re putting together a short survey about people’s experiences with chemistry experiments and synthesis, and thought this would be a good place to ask :)

If you’re an undergrad, grad student, PhD student, postdoc, professor, or working in industry and have spent some time in a chem lab, we’d really appreciate your input.

It should only take around 3–4 mins. We’re mainly asking about how you usually approach experiments, what parts take the most time, and what tends to be annoying/difficult along the way.

As a small thank you, we’ll randomly pick 4 people to get a $10 gift card.

Survey:
https://docs.google.com/forms/d/e/1FAIpQLSeXlBX2rw84iRnEmKLlhXF6E3S3jm3KNcaqmzohVNn87512Fg/viewform

Thanks a lot to anyone who fills it out!! really appreciate it

I just made this 3D animation explaining the MOA of ATP Synthase

Everything here is created from scratch ( 3D , 2D , SFX , Composition)

I would really love to know what u think about it

Hi y'all! I have a BS in chemistry and I've been working in the pharma/supplement industry for about 6 years. Most of my jobs have been some flavor of chromatography, either GC or LC, and one with mass spec work. I've retained my typical lab and wet chem skills and am pretty good at troubleshooting chromatography.

Lately, I've been considering going back to school but I don't feel I remember enough from my undergrad to succeed. I use enough gen chem knowledge in my work that I still know that stuff but the higher level things I learned are... gone for the most part. I remember really loving advanced inorganic chem, symmetry and transformation matrices, but I couldn't tell you anything about it. I don't remember the math or the logic, I just remember enjoying it.

Organic chem was always hard for me but I retained more of that knowledge just because I work with it. Still, I doubt my skills when it comes to solving actual problems. Like, I know how reagents react with each other but I don't think I could sit down and write out all the mechanisms.

I really want to start independently studying what I learned during undergrad before attempting grad school but obviously, I no longer have access to the materials. I think I have an old gen chem textbook in a closet somewhere but I sold most of my other textbooks when I graduated. I found some old study notes but they're largely useless without any other context.

Does anyone have any tips and/or resources on how someone might re-learn undergrad-level chemistry knowledge? Specifically lecture work, since I still have my lab skills. I do think that with some practice, a lot of it will come back to me.

1H NMR (500 MHz, CDCl3) δ 7.24 (dd, J = 7.3, 1.5 Hz, 1H), 7.17 (td, J = 7.8, 1.5

Hz, 1H), 6.98 (td, J = 7.3, 1.0 Hz, 1H), 6.83 (dd, J = 7.8, 1.0 Hz, 1H), 5.38 (br s,

1H), 4.88–4.86 (m, 2H), 2.89–2.86 (m, 2H), 2.44–2.41 (m, 2H), 1.89 (s, 3H).

13C NMR (125 MHz, CDCl3) δ 153.2, 145.8, 130.0, 128.2, 127.1, 120.8, 115.2,

110.1, 37.6, 28.4, 22.6. IR (thin film) 3424, 3072, 1648, 1236. HRMS (ESI) calcd

for [C11H14O – H]− 161.0972, found 161.096

I tried all the tables I can find, but it doesnt gimme this^

Left this beaker with a small amount of copper (II) sulfate for a while. At least it looks cool.